The pneu-Nimbus operation demo Watch Now

Butterfly heater at ETH Zurich Learn More

Installation video of the Nimbus system on an OrbiTrap MS Watch Now

Providing robust solutions to proteomic mass spec research challenges
Applications
Biomarker Discovery      
  • NanoLC and MicroLC for Increased Peak Resolution and Sensitivity
  •      
  • Programmable Voltage for Optimizing Charge States for MS/MS Sensitivity
  •      
  • Minimal Sample Consumption
  •      
  • Fast method development with programmable voltage and dual column capabilities


  • The AutoNano is uniquely suited for obtaining maximum sensitivity of peptide biomarkers. Biomarkers, useful for understanding medical disorders and the effectiveness of treatment, are generally present in biological matrices at <1pg/mL levels. Increasing sensitivity through the use of both nanoLC-MS and microLC-MS, and the optimized programmable voltage of multiply charged peptides allow the maximum obtainable sensitivity in targeted MS/MS analyses. This chromatograms below were obtained by the AutoNano’s programmable high voltage power supply which drives multiply charged peptides to the highest charge state in conjunction with an optimization of capillary voltage, cone voltage, and mobile phase composition for each peptide in a chromatographic method.
    Biomarker
    Printer-friendly (PDF)

    Nanospray analysis of neuropeptides
    Angiotension II, Leu-enkephalin, Met-enkephalin, a-Endorphin
    Method development - Programmable Voltage Optimization
    Leu-enkephalin
    Biomarker
    Printer-friendly (PDF)
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    "I'm very satisfied those (eFrit) columns. Resin was very efficiently packed without any stopping,"
    -Lee Hyoung-Joo, Yonsei Proteomix Research Center, Seoul, Korea

    "The carryover issue is definitely gone; I keep the temp at 40C, and it only takes one blank run to get rid of carryovers. I like the column heater."
    -Eric Chan, PhD, Constellation Pharmaceuticals

    "The µAutoNano dual-column source has in effect added an extra OrbiTrap and nanoflow pump to my lab without extra space and maintenance, and the column heater has allowed us to run analyses on 29 cm long Halo columns without a uPLC.  This has represented a huge cost savings for the lab."
    -Stephen Master, MD, Ph.D., University of Pennsylvania School of Medicine

    "Phoenix S&T provides great products and customer care for nanoLC-MS. I use their nanospray source for the Thermo LTQ and TSQ MS."
    Kwasi Mawuenyega, Ph.D., Washington University


    Play MovieVideos
    The Nimbus dual-column source in action

    Dual-column Spray: Automated Column Switching
    Live video shows automatic column switching. A new column is positioned, the spray purges and clears for virtually uninterrupted electrospray.
  • SureSpray(TM) plastic nozzle spray: non-clogging, robust spray

    Jun 4-Jun 8, 2017 - 65th ASMS Conference on Mass Spectrometry: Indianapolis, IN.

    Visit Phoenix S&T at Booth #520

    and see the new robust non-clogging, ultra-stable micropray system for the Thermo Easy-spray source! Also the pneu-Nimbus and Easy-Spray compatible column heater!


  • Come back soon to see our newly re-designed website with on-line shopping of some of our consumable products!

    More product information or pricing, please click here.

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    f. (610) 876.6084
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    website: www.phoenix-st.com