Phoenix S&T’s dual-column Nimbus (motorized) and pneu-Nimbus (pneumatic) sources increase productivity up to 100%. A 1D+ or 2D nanoLC pump is all is needed to duplicate the efficiency of you existing nanoLC-MS setup. Columns and emitters are thoroughly cleaned before each analysis to eliminate carry-overs. While one column is being washed and loaded, the other column is in front of the mass spectrometer doing analysis. There is no more down-time for the nanoLC-MS system. The column switching and sheath gas drying of the emitters are controlled by an on-board microcontroller without the need of an external computer and subsequent problem-prone integration with the data system. The mass spec’s data system controls everything related to the analysis, as it is normally done. It is set-and forget.
Our basic single-column source is easy to use, has added functionalities such as sheath-gas enabled for microspray applications, and can be upgraded to dual-column.
Our column heaters are custom-made for your columns so that they can be placed directly in front of the mass spec inlet. Even with such dedication to each researcher’s specific need, the heater and controller together are priced scarcely more than a single long column. Today our column heaters: the pencil heater, butterfly heater and jailbreak heater are the most widely used capillary column heaters in the world.
Our nanospray emitters PST-seTips, are laser-pulled with a new technique to give a stubby tip profile (the taper is ~0.5 mm from the tip to the capillary diameter of 360 um. The short, strong taper makes the emitters robust and non-clogging. The flow rate range of the new seTip is from sub-nanoliter/minute to under 10 uL/min. The spray is cone-jet mode even at the higher range of the flow rates without sheath gas, which results in the best ionization and vaporization conditions for the analytes in the buffer. Negative ion spray without the interference of corona discharge is also facilitated.
Fused silica emitters have been the industry standard. Our new shape improves on the long standing drawbacks of fused silica silica–the clogging and tip changing during spray.
We also offer the polypropylene PST-noz emitter which is primarily optimized for sub-microliter/minute flowrates. The manipulation of interfacial property of the polypropylene nozzle is what enables the superb spray performance of the nozzle emitter. The nozzle emitter is indispensable for spraying analytes in complex matrices such as serum and plasma, or unprocessed plant extracts or fermentation broths. They are virtually impossible to blog!