The pneu-Nimbus operation demo Watch Now
Butterfly heater at ETH Zurich Learn More
Installation video of the Nimbus system on an OrbiTrap MS Watch Now
Clog Resistant Spray Devices
When compared to conventional designs of nanospray sources, which typically have a long, narrow bore tube of a few microns in diameter, and are made of materials such as silica, the polypropylene nozzle, with its relatively large orifice and conical channel, are far less likely to clog even by diluted but unfiltered serum or plasma samples, yet the hydrophobic plastic material construction of the nozzle allows nanospray at very low flow rate (<50nL/min).
Microspray and Nanospray in a single spray emitter
Nanospray and microspray provide high ionization efficiency and consumes mere nanoliters of samples. Low flow rate (under 50 nL/min) nanospray, in addition to the obvious advantage of conserving scarce samples, offers desirable performance advantages such as higher sensitivity and higher tolerance for salts in the samples. However, many LC methods prefer flow rates at 1 ÁL/min or higher. Both the nanospray nozzles and the polymeric polytip can be used for the entire range of these flow rates. For flow rates in the microspray range, i.e. > 1 ÁL/min, a concentric flow of nitrogen gas ensures effective ionization of the eluates.
"I'm very satisfied those (eFrit) columns. Resin was very efficiently packed without any stopping,"
-Lee Hyoung-Joo, Yonsei Proteomix Research Center, Seoul, Korea
"The carryover issue is definitely gone; I keep the temp at 40C, and it only takes one blank run to get rid of carryovers. I like the column heater."
-Eric Chan, PhD, Constellation Pharmaceuticals
"The µAutoNano dual-column source has in effect added an extra OrbiTrap and nanoflow pump to my lab without extra space and maintenance, and the column heater has allowed us to run analyses on 29 cm long Halo columns without a uPLC. This has represented a huge cost savings for the lab."
-Stephen Master, MD, Ph.D., University of Pennsylvania School of Medicine
"Phoenix S&T provides great products and customer care for nanoLC-MS. I use their nanospray source for the Thermo LTQ and TSQ MS."
Kwasi Mawuenyega, Ph.D., Washington University
The Nimbus dual-column source in action
Jun 5-Jun 9, 2016 - 64th ASMS Conference on Mass Spectrometry: San Antonio, TX.
Visit Phoenix S&T at Booth #303and see the new robust non-clogging spray emitters, pneu-Nimbus and Easy-Spray compatible column heater!